On the need to monitor more than one cerebral artery in future cerebrovascular studies…

I just read another interesting manuscript by Ogoh’s team entitled Regional redistribution of blood flow in the external and internal carotid arteries during acute hypotension.

In that study, the authors were interested in the changes in external carotid artery (ECA) blood flow following acute hypotension and whether the latter changes influence internal carotid artery (ICA) blood flow regulation. The authors observed clear regional differences in ICA and ECA blood flow in response to acute hypotension (using the thigh cuff method). Indeed, while ICA blood flow lowered in response to hypotension and then quickly recovered to baseline levels, ECA blood was also reduced but that reduction in blood flow was maintained during the entire recovery period.

According to the authors

This finding suggests that the selective redistribution of blood flow from the ECA to support the recovery of ICA blood flow may reflect a neuroprotective mechanism that serves to optimize intracranial blood flow and oxygenation during acute hypotension.


In this sense, the peripheral vasculature associated with the ECA may be an important and hitherto unrecognized site that contributions toward intracranial cerebral blood flow regulation.

This is really interesting.

However, the aim of this small post is rather to point out that with the publication of such results, coupled to those suggesting regional differences in cerebral blood flow distribution during exercise, cerebral autoregulation and cerebrovascular reactivity to CO2, will it still be possible to monitor blood flow/blood flow velocity in only one cerebral artery (the beloved MCA for example) in upcoming studies ??

In a recent review on cerebral autoregulation, we have suggested that

New technologies permit a more integrative evaluation of the cerebrovascular function in response to different challenges. Future studies need to consider regional differences in CBF regulation during blood pressure manipulation

Let me revise that last sentence…

Future studies will have to consider regional differences in CBF regulation…whatever thinkable experimental conditions.

Trying to publish a story focusing on only one cerebral artery will most likely become, in a near future, as hard as to publish a vasopressor story using near-infrared spectroscopy alone…

What do you think?


9 thoughts on “On the need to monitor more than one cerebral artery in future cerebrovascular studies…

  1. It’s not my first time to pay a visit this web page, i am visiting
    this web page dailly and get fastidious facts from here daily.

  2. Excellent post. I used to be checking constantly this blog and I am impressed!
    Very useful information specially the last phase 🙂 I maintain such information much.
    I used to be looking for this particular info for a long time.
    Thanks and good luck.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s